Study 1. Central Findings:Evidence AmDTx improves mental health and cognitive performance | “Acceptance”and “Awareness” are important elements of overall mental wellbeing, specifically referring to acceptance of distressing events or thoughts and awareness of internal thoughts and sensations as well as the outside world. Separately, “Conflict Effect” is an important measure of the cognitive capacity to monitor and respond appropriately to conflicting information. The “z-score” is a statistical measure used here to indicate how that data are to the population average. These data show that AmDTx relative to placeboincreases both acceptance and awareness, and thus mental wellbeing. The data also show that AmDTx, but not placebo, enhances the ability to monitor conflict, and therefore cognitive performance. Long-termbenefits of the mobile health platform were also observed for stress and mood.This trial was also an early demonstration of the platform’s capacity to monitory patient health remotely at scale.

Walsh et al. (2019) Effectsof a Mindfulness-Meditation App on Subjective Well-Being: An Active Randomized Controlled Trial and Experience Sampling Study. JMIR Mental Health, 6(1).

Study 2. Central Findings: Evidence AmDTx improves athleticism | The relationship between mobile mindfulness training and interoceptive awareness. Threeweeks of mindfulness training through a mobile app led to a significant increase in self-reported interoceptive awareness in participants relative to the active control. Error bars represent the standard error of the mean (SEM). The effect of the intervention vs. active control using a factor analysis revelaed a Condition x Session interaction for the effort and distress tolerance measure, where effort and distress tolerance increased for the MT group relative to active control. CT = Control Group; MT = Mindfulness Training Group

Rai et al. (2024) Working Smarter, Not Harder: The effects of a digital therapeutic on exercise performance in an active RCT. Mindfulness, (submitted).